Stadsmiljö gör människan känsligare för stress

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Att växa upp och leva i städer gör människor känsligare för social stress än att leva på landsbygden, något som skulle kunna bidra till att förklara att det är större risk att drabbas av psykisk sjukdom om man lever i städer. (Av Andreas Meyer-Lindenberg och medarbetare, 2011.)

Titel: City living and urban upbringing affect neural social stress processing in humans

Författare: Lederbogen, Florian, Kirsch, Peter, Haddad, Leila, Streit, Fabian, Tost, Heike, Schuch, Philipp, Wust, Stefan, Pruessner, Jens C., Rietschel, Marcella, Deuschle, Michael, Meyer-Lindenberg, Andreas

Publikation: Nature

Volym: 474

Nummer: 7352

Sidor: 498-501

Publicerad: 2011

Sammandrag: More than half of the world’s population now lives in cities, making the creation of a healthy urban environment a major policy priority1. Cities have both health risks and benefits1, but mental health is negatively affected: mood and anxiety disorders are more prevalent in city dwellers2 and the incidence of schizophrenia is strongly increased in people born and raised in cities3, 4, 5, 6. Although these findings have been widely attributed to the urban social environment2, 3, 7, 8, the neural processes that could mediate such associations are unknown. Here we show, using functional magnetic resonance imaging in three independent experiments, that urban upbringing and city living have dissociable impacts on social evaluative stress processing in humans. Current city living was associated with increased amygdala activity, whereas urban upbringing affected the perigenual anterior cingulate cortex, a key region for regulation of amygdala activity, negative affect9 and stress10. These findings were regionally and behaviourally specific, as no other brain structures were affected and no urbanicity effect was seen during control experiments invoking cognitive processing without stress. Our results identify distinct neural mechanisms for an established environmental risk factor, link the urban environment for the first time to social stress processing, suggest that brain regions differ in vulnerability to this risk factor across the lifespan, and indicate that experimental interrogation of epidemiological associations is a promising strategy in social neuroscience.

Länk till original: http://dx.doi.org/10.1038/nature10190

Kategori: Arkitektur/stadsbyggande Hur hjärnan påverkas av ... Psykisk ohälsa

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